HealthWatch: Talking Autism: Boys Vs Girls

Health Watch

Philadelphia, Pa. (Ivanhoe Newswire) – Young boys in America are diagnosed with autism four times more often than girls, and researchers want to figure out why. It turns out girls use different kinds of words to retell a story than do boys. Words like ‘I think’ and ‘I feel.’ And that very language separator may mask autism in girls.

She’s bright and creative. And eleven-year-old Caroline Robb is autistic … which is challenging when she’s trying to fit in with other pre-teens in middle school.

“I used to run around by myself on the playground. I didn’t really get to talk to a lot of people. I kind of sat out a lot,” explained Robb.
She uses ‘feeling’ words to describe her situation, and that’s what differentiates her from autistic boys. They usually only use concrete words.

“Girls with autism will tend to kind of hover near social groups out on the playground. And, I think that kind of behavior, the hovering near, can make it complicated for people when they’re looking for autism,” said Julia Parish-Morris, PhD, Scientist, Center for Autism Research at CHOP.

Even Caroline’s parents who had her diagnosed at four, first noticed behavioral, rather than language, differences.

“It definitely was not language that took us there. It was behaviors, body movements and learning things,” Elizabeth Robb, Caroline’s mom, said.

“When you separate out the kids with autism into boys and girls, the girls with autism actually talked a lot more like the typical kids than the boys,” continued Dr. Parish-Morris.

But here’s what to listen for in boys and girls: fewer emotional phrases like ‘I feel,’ or ‘she thinks.’ more concrete words and kids who are laser-focused on only one subject.

“It’s not universal to all girls, neither is it exclusionary of all boys … but to really pay attention to the other more subtle things that might be showing up in girls and young children that have autism,” stated Dr. Parish-Morris.

More research needs to be done to determine exactly why boys are diagnosed so much more often than girls. But experts think linguistics hold major clues. Dr. Parish-Morris says ideally, she’d like to see society become inclusive of autistic people no matter their language style.

Contributors to this news report include: Donna Parker, Field Producer; Jamison Koczan, Editor; and Roque Correa, Videographer.

BACKGROUND: Autism spectrum disorder (ASD) is a developmental disability that can cause significant social, communication and behavioral challenges. People with ASD may communicate, interact, behave, and learn in ways that are different from most other people. The learning, thinking, and problem-solving abilities of people with ASD can range from gifted to severely challenged. A diagnosis of ASD now includes several conditions that used to be diagnosed separately: autistic disorder, pervasive developmental disorder not otherwise specified (PDD-NOS), and Asperger syndrome. These conditions are now all called autism spectrum disorder. About 1 in 59 children has been identified with ASD, and it is about 4 times more common among boys than among girls. Studies have shown that parents of children with ASD notice a developmental problem before their child’s first birthday. Concerns about vision and hearing were more often reported in the first year, and differences in social, communication, and fine motor skills were evident from 6 months of age.
(Source: https://www.cdc.gov/ncbddd/autism/facts.html)

AUTISM: BOYS VS. GIRLS: Between four and five times as many boys as girls are diagnosed with ASD each year. According to some researchers, the reason is that autism is an excessive expression of those aspects of brain development that are already pronounced in the male brain. The extreme male brain theory assumes that it is an overdevelopment in the male traits of cognition that causes ASD patients to over-systematize, leading to a breakdown of verbal and social capacities. Other studies have found correlations between fetal testosterone levels and ASD. Researchers in Canada undertook a genetic study of ASD patients and found that around one percent of the males tested had a mutation in a certain gene on their X-chromosome. If the mutation were found to be linked to ASD it could explain some of the preponderance of ASD among boys. Even more recently, scientists in Germany found a positive correlation between a thin cortex and the likelihood of an ASD diagnosis. Since women reliably have greater cortical thickness than men, this could indicate that the male brain is simply more vulnerable to whatever structural changes bring about ASD.
(Source: https://www.appliedbehavioranalysisedu.org/why-are-boys-more-likely-to-have-autism/)

POTENTIAL TREATMENT: A breakthrough in finding the mechanism and a possible therapeutic fix for autism and intellectual disability has been made by a University of Nebraska Medical Center researcher and his team at the Munroe-Meyer Institute (MMI). Woo-Yang Kim, PhD, associate professor, developmental neuroscience, led a team into exploring a genetic mutation that reduces the function of certain neurons in the brain. “This is an exciting development because we have identified the pathological mechanism for a certain type of autism and intellectual disability,” Dr. Kim said. Recent studies have shown that the disorder occurs when a first-time mutation causes only one copy of the human AT-rich interactive domain 1B (ARID1B) gene to remain functional, but it was unknown how it led to abnormal cognitive and social behaviors. The next steps are to further refine the specific mechanism for autism and intellectual disability and to identify which of the many GABA neurons are specifically involved.
(Source: https://medicalxpress.com/news/2017-11-breakthrough-potential-treatment-autism-intellectual.html)

? For More Information, Contact:

Julia Parish-Morris, PhD Ben Leach, Senior Public Relation Specialist
parrishmorrisj@email.chop.edu leachb@email.chop.edu / (267) 426-2857

Free weekly e-mail on Medical Breakthroughs from Ivanhoe. To sign up: http://www.ivanhoe.com/ftk

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