The City of Kaukauna Fire Department was sent to 557 Willow Drive for reports of a house fire Saturday just after six in the morning.
When they arrived, they found heavy smoke coming from all eves and roof vents.
Windows were blacked out because of the smoke and no obvious fire was found on the exterior of the home.
Crews entered and found heavy smoke and high heat with fire burning through the floor, which had already collapsed.
The fire was also found in the interior basement stairway.
No one was reported inside the residence at the time of the fire.
Fire crews established a plan of attack on the exterior of the home, since areas inside were collapsed.
They were able to bring the fire under control in two hours. Personnel remained on scene for four more hours until they determined the fire was completely out.
The fire is not deemed suspicious and an investigation will be initiated once the integrity of the building is evaluated and secured.
Damage to the home is estimated $160,000.